The Palestinian-born 40-year-old reached the 8,848-metre peak after 51 days of climbing, and nearly two years of preparation.
She said: ‘Becoming the first Arab woman to reach the top of the world was an enormous thrill and a great privilege.
‘I will never forget the moment when my dream became reality, when I saw the prayer flags flapping in the thin air, marking the summit of the greatest mountain on earth.’
She scaled the mountain with four others, three of whom successfully reached the summit.
After reaching the the top, she unravelled a banner bearing the flags of Arab countries.
She added: ‘I would like to share this triumph with the Palestinian people and all Arabs – especially all the Arab women, young and old – who continue to contribute to the peace and stability of the region we all call home.’
In 2003, Ms al-Houby became the first Arab woman to reach Everest Base Camp, the first to ascend Mount Elbrus, the highest point in Europe, and the first Palestinian woman to climb Mount Kilimanjaro, Africa’s highest peak.
To date, she has successfully reached the summit of the highest mountains on five of the world’s seven continents.
Since Mount Everest was first scaled by Sir Edmund Hillary and Tenzing Norgay in 1953, approximately 100 women have accomplished the feat.